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KMID : 0380620150470040517
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Korean Journal of Food Science and Technology
2015 Volume.47 No. 4 p.517 ~ p.524
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Protective Effect of Angelica keiskei Juice and Oenanthe javanica DC Juice on Oxidative Stress
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Lee Doo-Jin
Lee Jin-Ha
Lee Ok-Hwan
Kim Boh-Kyung
Park Kun-Young
Kim Jong-Dai
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Abstract
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The objectives of the present study were to investigate the protective effects of Angelica keiskei juice and Oenanthe javanica juice against oxidative damage in LLC-PK1 renal epithelial cells and to evaluate their free radicalscavenging activities. Both A. keiskei juice and O. javanica juice showed a strong in vitro antioxidant activities such as α, α-diphenyl-β-picrylhydrazyl (DPPH), nitric oxide (NO), O2 ?, and ·OH radical-scavenging activities. The LLC-PK1 cells showed significant lipid peroxidation and cell death due to oxidative stress when it was induced by 2, 2'-azobis (2- amidinopropane) dihydrochloride (AAPH), sodium nitroprusside (SNP), pyrogallol, and 3-morpholinosydnonimine (SIN-1). Treatment with both A. keiskei juice and O. javanica juice significantly increased cell viability and inhibited lipid peroxidation. These results suggest that A. keiskei juice and O. javanica juice are potential natural antioxidants.
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KEYWORD
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Angelica keiskei juice, Oenanthe javanica DC juice, oxidative stress, vegetable juice, antioxidant
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